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peptic ulcer

   Also found in: Dictionary/thesaurus, Medical, Wikipedia, Hutchinson 0.07 sec.
peptic ulcer: see ulcer ulcer, open sore or circumscribed erosion, usually slow to heal, on the skin or mucous membranes. It may develop as a result of injury; because of a circulatory disturbance, e.g.
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peptic ulcer

Sore that develops in the mucous membrane of the stomach (more frequent in women) or duodenum (accounting for 80% of ulcers and more frequent in men) when its ability to resist acid in gastric juice is reduced. It causes burning ache and hungerlike pain. Ulcers can bleed, perforate the abdominal wall, or block the gastrointestinal tract. Stress and diet were blamed until Helicobacter pylori bacteria and long-term use of aspirin and similar drugs were shown to be the two major causes. The former is treated with combination drug therapy and the latter by stopping the causative drugs if possible or with drugs that reduce acid production. A rare cause is Zollinger-Ellison syndrome, in which a tumour causes increased acid secretion. Cigarette smoking slows healing and promotes recurrence.


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After confounding variables were adjusted for, the independent risk factors were age, duration of hospitalization, peptic ulcer disease, and receipt of fluoroquinolones.
Tokyo, Japan, June 19, 2006 - (JCN) - Takeda Pharmaceutical announced on June 16 that it obtained additional approval for Takepron (lansoprazole) Capsules 15/ OD Tablets, its proprietary peptic ulcer agent, from the Ministry of Health, Labor and Welfare.
While licorice is useful for treating peptic ulcer, the treatment should not exceed four to six weeks because of the known side effects.
 
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